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An Integrated Cell-Death Program Defines Aggressive Prostate Cancer by Coupling Ezrin to the Hippo–YAP/TAZ Axis

Xing Luo Ze-Yu Huang Min Deng Jin-Gui Liu Chao-Yu Liao You-Hao Yang Zhao-Yu Meng Jian-Xu Yuan Jia-Hao Xu Yuxuan Liu Qiu-Lin Wang Zhi-Hao Wang Hao Li Rong-Hui Shi Han Zeng Shuai Su Liang Liu Ji Zheng
Jul 2026 · Annals of Surgical Oncology · Vol 33, pp. 9431 - 9441 · 0 citations · 28 references
Medicine

TL;DR

The AEN score is a robust prognostic tool linking PCD activity to PCa aggressiveness and immune evasion and EZR emerges as a functional effector and potential therapeutic target acting through Hippo signaling in PCa.

DOI PubMed Semantic Scholar
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