Author

Jiahao Xu

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Jul 2026

An Integrated Cell-Death Program Defines Aggressive Prostate Cancer by Coupling Ezrin to the Hippo–YAP/TAZ Axis

The AEN score is a robust prognostic tool linking PCD activity to PCa aggressiveness and immune evasion and EZR emerges as a functional effector and potential therapeutic target acting through Hippo signaling in PCa.

Xing Luo, Ze-Yu Huang, Min Deng et al. · Annals of Surgical Oncology · 0 citations

Review Open access 2026

Therapeutic oligonucleotides revisited: Focus on siRNA and antisense technologies

This review first provides a concise overview of the mechanistic principles underlying oligonucleotide function and commonly employed chemical modification techniques, and highlights recent advancements in receptor-mediated delivery systems for extrahepatic targeting, and dual-targeting oligonucleotide engagement strat...

Liuhai Chen, Jiahao Xu, Jin Li et al. · The Innovation Drug Discover... · 2 citations