Author

Jia-Juan Guo

3 papers indexed here

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Open access Aug 2026

Dynamic frailty and incident cardiometabolic multimorbidity in Chinese adults

Cardiometabolic multimorbidity (CMM), commonly defined as the co-existence of at least two of diabetes, heart disease, and stroke, is associated with substantially increased mortality [1, 2]. Frailty is a multidimensional state of reduced physiological reserve and may change over time [3–6]. However, evidence linking b...

Hao Chen, Sheng-Nan Yue, Zhao-Zhi Zhang et al. · Archives of Medical Science · 0 citations

Open access Oct 2026

Living environmental quality and incident cardiometabolic multimorbidity: a prospective cohort study in China

Cardiometabolic multimorbidity (CMM) is an increasing public health concern in ageing populations. Although individual residential environmental factors have been linked to cardiometabolic health, the association of multidimensional living environmental quality with incident CMM remains unclear. We aimed to const...

Hao Chen, Sheng-Nan Yue, Sheng-Yan Hou et al. · BMC Public Health · 0 citations

Open access Sep 2026

Unraveling shared immunotoxicological mechanisms linking exposure to PPCPs with Alzheimer's disease and atherosclerosis: integrative multi-omics, network toxicology, and experimental validation.

BACKGROUND Pharmaceuticals and personal care products (PPCPs) are pseudo-persistent contaminants with potential exposure risks. Atherosclerosis (AS) and Alzheimer's disease (AD) share neurovascular and myeloid-immune remodeling, but whether chemical-target networks associated with exposure to PPCPs converge on shared m...

Zhian Chen, Tian-Ying Liu, Jian-Kang Wang et al. · Environment International · 0 citations