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Sponsored Design Multi-Agent AI Systems Using MCP and A2A: Engineer your own Pyt Design Multi-Agent AI Systems Using MCP and A2A: Engineer your own Pyt

Author

Jia-Lin Han

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Open access Jul 2026

CAPNS1 restoration partially alleviates mitochondrial dysfunction and synaptic deficits in Alzheimer's disease through the Ca2⁺-CaMKIIβ-MAPK-PGC-1α axis.

Significantly, neuronal-specific CAPNS1 upregulation in APP/PS1 transgenic mice markedly improved mitochondrial cristae integrity, reversed hippocampal long-term potentiation deficits, increased dendritic spine density, and partially alleviated spatial memory deficits in behavioral tests.

Jia-Lin Han, Shuang Wu, Xiaolin Cui et al. · 0 citations
Aug 2026

Transcriptome-wide association analysis of Alzheimer’s disease: construction and clinical validation of transcriptomic risk scores

The AD-specific transcriptomic risk scores (TRSs) developed in this study shows promising clinical utility in AD diagnosis, differential diagnosis, and risk prediction, providing valuable translational medical evidence for early screening and precision prevention of Alzheimer's disease.

Peng-Fei Zhang, Zhongqian Juan, Jia-Lin Han et al. · 0 citations

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