Dioscin (C45H72O16, DIO) is a naturally occurring steroidal saponin widely distributed in medicinal plants of the Dioscoreaceae, Liliaceae, and Fabaceae families. Given its remarkable hepatoprotective properties, DIO has attracted increasing attention in recent years. Based on literature retrieved from Web of Science,...
Jia Liu, Ru-Lan Sun, Jie Huang et al.· Frontiers in Pharmacology· 0 citations
Results demonstrate that SREBF2 mitigates MI-induced HF by activating the Cav-1/PINK1/Parkin axis to promote mitophagy and inhibit ferroptosis, and identify SREBF2 as a promising therapeutic target in heart failure.
Jia Li, Jia Liu, Fan-Yan Luo et al.· Journal of molecular medicin...· 0 citations
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