Jul 2026
Structure-alignment-driven cross-graph modeling for functional RNA design
An RNA design approach, AlignIF, that leverages multiple structure alignment with cross-graph modeling and carefully hand-designed features to capture evolutionarily conserved structural patterns at the structural level, facilitating RNA sequence design outperforms existing state-of-the-art methods in test sets.
Sheng-Fan Wang, Jun Wang, Xiao-Jian Liu et al.
· Nature Computational Science · 2 citations
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