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Author

Jiandong Bao

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Jul 2026

Inhibition of TGF-β1/Smad signaling reverses the dedifferentiated phenotype of thyroid cancer cells in three-dimensional culture

A three-dimensional culture model of TPC-1 thyroid cancer cells was developed and identified transforming growth factor beta 1 (TGF-β1) as a potent inducer of thyroid cancer dedifferentiation, establishing TGF-β1 as a therapeutic target in thyroid cancer.

Li Zhang, Wen-Jing Gao, Shi-Chen Xu et al. · 0 citations

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