Author

Jian-Hui Guo

3 papers indexed here

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Sep 2026

Exposure-wide association study-assisted identification of modifiable factors for depression prevention.

Depression is a leading cause of disability worldwide, yet evidence on modifiable factors remains limited and fragmented. Using UK Biobank data, we comprehensively evaluated 218 modifiable factors across eight predefined domains and integrated polygenic risk scores to inform prevention. Among 290,278 participants (mean...

Jian-Hui Guo, Ya-Wen Zheng, Fei-Fei Si et al. · Psychiatry Research · 0 citations

Open access Sep 2026

Burden of mental disorders: Evidence from the Global Burden of Disease Study 2023.

BACKGROUND Mental disorders contribute significantly to the global disease burden, with marked regional variations. This study provides the most up-to-date assessment of trends in the burden of mental disorders worldwide and in China and compares the burden of mental disorders between China and other regions. METHODS...

Jian-Hui Guo, Huan Wang, Yan-Hua Chen et al. · Chinese Medical Journal · 0 citations

Open access Aug 2026

Association Between PM2.5 Components and Cerebral Hypoperfusion: A Mediation Role of Inflammatory Biomarkers

Cerebral hypoperfusion, an acute manifestation of intracranial arterial stenosis (ICAS), is particularly concerning among older East Asian adults given its high prevalence. Systemic inflammation triggered by PM2.5 exposure has been linked to cerebrovascular diseases, yet evidence on its specific components of hypoperfu...

Xing-Yan Xu, Xinyue Lu, Nan Wang et al. · European Journal of Neurolog... · 0 citations