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#protein folding Oct 2026

Programming Hydrophobic Nanocavity of DNA Frameworks for Ultrastable Fluorescent Imaging

ABSTRACT Fluorescent proteins (FPs) are widely used in biological imaging, yet their limited programmability restricts adaptability for advanced nanoscale applications. Synthetic molecular containers offer designable cavities but struggle to simultaneously achieve large dimensions, biocompatible interfaces, and precise...

Tingting zhai, Lingyu Feng, Xinyi Cheng et al. · 0 citations
#protein folding Oct 2026

Programming Hydrophobic Nanocavity of DNA Frameworks for Ultrastable Fluorescent Imaging.

Fluorescent proteins (FPs) are widely used in biological imaging, yet their limited programmability restricts adaptability for advanced nanoscale applications. Synthetic molecular containers offer designable cavities but struggle to simultaneously achieve large dimensions, biocompatible interfaces, and precise microenv...

Ting-Ting Zhai, Ling-Yu Feng, Xin-Yi Cheng et al. · 0 citations
#protein folding Sep 2026

Myelin-Inspired 3D PEGylation of Framework Nucleic Acids Enables Simultaneous Long Circulation and Rapid Renal Clearance.

This work establishes spatial conformation as a programmable parameter for regulating nanoparticle biodistribution and clearance, thereby shifting the design paradigm from compositional adjustment to architectural control and opening avenues for targeted delivery, imaging, and immunotherapy.

Qian Chen, Fei Ding, Shuang-Ye Zhang et al. · 0 citations

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