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Author

Jiang-Ning Song

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Review Open access Sep 2026

The evaluation crisis in artificial intelligence‐driven computational biology: Pitfalls and solutions

Artificial intelligence (AI) is rapidly transforming computational biology. However, closer scrutiny reveals that many reported results do not hold under rigorous evaluation. This paper identifies prevalent, recurring issues in the field, including narrow datasets, hidden confounders that make supposedly independent...

T. F. Khang, Joshua W. K. Ho, Lin Hou et al. · 0 citations
#protein folding Open access Sep 2026

Simplifying in silico protein evolution with minimal screening by unZipro.

UnZipro is presented, an efficient, scalable, and generalizable framework for zero-shot, in silico protein evolution, that integrates a compact, pre-trained inverse folding model with meta-learning to derive family-specific fitness landscapes.

Zhao-Hui Qin, Sanzeng Zhao, Zhao-Long Deng et al. · 0 citations

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