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Open access Jul 2026

WGCNA-based identification and experimental validation of TOP2A as a key regulator of ferroptosis in sepsis-associated acute respiratory distress syndrome

The transcriptional regulation of topoisomerase II alpha (TOP2A) by GATA binding protein 2 (GATA2) was verified using JASPAR prediction, chromatin immunoprecipitation (ChIP), and dual-luciferase reporter assays.

Na Wang, Kangbo Li, Chuan-Yong Gong et al. · 0 citations

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