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Jul 2026

Structure-alignment-driven cross-graph modeling for functional RNA design

An RNA design approach, AlignIF, that leverages multiple structure alignment with cross-graph modeling and carefully hand-designed features to capture evolutionarily conserved structural patterns at the structural level, facilitating RNA sequence design outperforms existing state-of-the-art methods in test sets.

Sheng-Fan Wang, Jun Wang, Xiao-Jian Liu et al. · 2 citations · ⚡1

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