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Author

Jie Wu

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Open access Sep 2026

SelO functions as a tumor suppressor through AMPylating Cdk5rap3.

A role for protein AMPylation in cell signaling and cancer progression is revealed and is shown to be related to cell proliferation and TGF-β-mediated migration.

Li Wu, Jie Wu, Wen-Qiang Xie et al. · 0 citations
Aug 2026

Integrated genome-wide high-throughput screening and functional validation identifies Sm proteins as essential splicing regulators for gastric cancer progression

Integrating genome-wide CRISPR-Cas9 and RNA interference proliferation screening data from human GC cell lines, the integrated approach defines the Sm proteins as essential for GC progression, highlighting the therapeutic potential of targeting this splicing pathway.

Dai-Hong Chen, Jie Wu, Yonggang Zhang et al. · 0 citations

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