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Sponsored AI AM CLAUDE, A Beginner's Guide: Learn the basics of working with AI AI AM CLAUDE, A Beginner's Guide: Learn the basics of working with AI

Author

Jing-Jing Li

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#gene editing Oct 2026

Molecular dynamics simulation and QM/MM study of IscB-ωRNA complex.

The CRISPR-Cas9 system's gene-editing fidelity relies on the HNH nuclease domain's ability to hydrolyze DNA via metal-ion catalysis. While IscB-ωRNA variants offer advantages for viral delivery due to their small size, their editing efficiency is much lower than that of Cas9. The understanding of how HNH-domain dynamic...

Amina Abula, Gang-Gang Bai, Jing-Jing Li et al. · 0 citations
Open access Sep 2026

SynerHyper: Predicting Anticancer Drug Synergy for Lung Cancer Using Uni-Mol Enhanced Hypergraph Neural Networks and Multimodal Fusion

SynerHyper provides a lung cancer-specific computational framework for prioritizing candidate drug combinations for downstream experimental validation and an accessible online prediction server that integrates three-dimensional molecular representations, transcriptomic profiles, hypergraph learning, and ensemble fusion...

Chuan-Ce Sun, Ling-Hao Zhang, Xiao-Tang Huang et al. · 0 citations

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