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Jing-Xuan Wang

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Open access Oct 2026

Plasma proteomics identifies four candidate biomarkers associated with macrovascular complications in type 2 diabetes: evidence from a clinical cohort and an animal model

To identify and validate plasma protein biomarkers for T2DM macrovascular complications through proteomic screening, clinical validation, and animal models. Plasma proteomics (4D-DIA, n = 6/group) was used to screen candidate proteins via differential expression, WGCNA, and PPI analyses. Candidates were vali...

Nuo Chen, Jing-Xuan Wang, Xiao-Jing Yuan et al. · 0 citations

Plasma proteomics identi fi es four candidate biomarkers associated with macrovascular complications in type 2 diabetes: evidence from a clinical cohort and an animal model

Four candidate proteins were prioritized: adenylosuccinate lyase (ADSL), galectin-3 (LGALS3), mannosyl ( a -1,3)-glycoprotein b -1,2-N-acetylglucosaminyltransferase (MGAT1), and V-set and immunoglobulin domain-containing protein 4 (VSIG4) and the four-protein panel showed good discrimination.

Nuo Chen, Jing-Xuan Wang, Xiao-Jing Yuan et al. · 0 citations

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