Open access
Sep 2026
Post-translational modifications of KRAS: from molecular regulation to therapeutic targeting
: The rat sarcoma virus (RAS) proteins are small GTPases that regulate cell signaling and are frequently mutated in human cancers. Their activity is mainly controlled by cycling between guanosine diphosphate (GDP)-bound and guanosine triphosphate (GTP)-bound states, which is regulated by guanine nucleotide exchange fac...
Ni Yao, Lu Yang, Ran-Ran Zhou et al.
· Advanced Cancer Research · 0 citations