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Author

Jonathan M. Grimes

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2 papers indexed here

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Open access Sep 2026

WDR82 code coordinates transcription and pre-mRNA 3′-end processing through regulated phosphorylation

Phosphorylation plays a central role in coordinating transcription with pre-mRNA maturation, yet the mechanistic understanding of how transcription is regulated by phosphorylation remains limited. The PP1 phosphatase removes Cdk9-dependent phosphorylation of Pol II and Spt5, triggering transcription termination. Here...

Alex Au, Abigail Southers, Krzysztof Kuś et al. · 0 citations
Open access Aug 2026

Influenza A virus initiates genome selection through promoter-dependent nuclear export

It is demonstrated that influenza virus initiates genome selection in the nucleus and reveal nuclear export as an early step in genome selection, and a promoter-dependent checkpoint is identified that links RNA promoter architecture and polymerase conformation to RNP export and packaging.

Kuang-Yu Chen, Alison Rep, L. Carrique et al. · 0 citations

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