A structure-aware generative AI framework for revealing functional relationships in protein families
Significance Protein databases contain millions of rapidly accumulating sequences, while increasingly accurate 3D structure predictions provide unprecedented data for analysis. Predicted structures can also be encoded using a structure-focused alphabet alongside standard amino acid (AA) representations. We introduce a...
Divyanshu Shukla, Jonathan Martin, F. Morcos et al.
· Proceedings of the National... · 0 citations