Author

Jorge A Yañez-Santos

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Open access Aug 2026

TagR, a newly identified member of the MarR family of transcriptional regulators, represses the NRPS operon in Klebsiella oxytoca

ABSTRACT Toxigenic Klebsiella oxytoca strains produce the pyrrolobenzodiazepine enterotoxins tilimycin (TM) and tilivalline (TV), which contribute to the development of antibiotic-associated hemorrhagic colitis. The biosynthesis of these toxins depends on the nonribosomal peptide synthetase (NRPS) operon located within...

Cristopher Perez, M. A. López-Luis, Carlos J Jiménez-Sánchez et al. · Microbiology spectrum · 0 citations

System CpxRA Negatively Regulates the Locus of Enterocyte Effacement of Enterohemorrhagic Escherichia coli Involving 32 σ and Lon protease RETRACTED: The Two-Component

The Galleria mellonella model of infection was used and the effect of the loss of the cpx and lon genes in EHEC’s ability to kill the larvae was found, suggesting that virulence in the G. mellonella model is T3SS independent and that CpxA modulates virulence through a yet unknown EHEC-speciﬁc factor.

Tracy L. Raivio, Jorge A. Girón, M. A. de la Cruz et al. · 0 citations