Multicomplex Integrative Structural Modeling of a Human Histone Deacetylase Interactome
Histone Deacetylase (HDAC) 1 and 2 are key enzymatic components in multiple large chromatin remodeling complexes including NuRD, SIN3, and CoREST. In addition, both HDAC 1 and 2 contain a large intrinsically disordered region (IDR) within their C-terminal domain (CTD). How HDAC1/2 assemble into these complexes and the...
Jules Nde, Kartik Majila, Rosalyn C. Zimmermann et al.
· Molecular & Cellular Proteom... · 0 citations