Author

Juan Chen

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Open access Jul 2026

Pharmacological manipulation of Sema4D by salvianolic acid A mitigates diabetic retinopathy via inhibiting PlexinB1/RhoA/ROCK/pMLC2 signaling cascade involved in endothelial dysfunction

Sal A treatment ameliorated retinal vascular abnormalities in diabetic mice, evidenced by increased VE-cadherin and NG2 expression, decreased α-smooth muscle actin (α-SMA) expression, and reduced acellular capillary formation, collectively restoring vascular integrity.

Weiwei Zheng, Ling Ning, Peiliang Shen et al. · Chinese Medicine · 0 citations

Open access Jul 2026

Study on the physicochemical properties of MSCs exosome-loaded viscous hydrogels and their mechanism of regulating angiogenesis

It is demonstrated that viscoelastic PEG–alginate hydrogels enhance the stability, cellular uptake, and pro-angiogenic efficacy of MSC-derived exosomes while providing cytoprotective effects, highlighting their potential as an effective delivery platform for angiogenesis-mediated regenerative therapies.

Xiao-Dong Yang, Jianqing Deng, Yu-Xing Zhang et al. · 3 Biotech · 0 citations