Pushing the limits of single-cell proteomics to investigate bacterial heterogeneity using bacSCP
Single-cell proteomics (SCP) has emerged as a powerful approach to quantify protein expression variability at cellular resolution, yet most state-of-the-art workflows are tailored to eukaryotic cells with only one study exploring how single bacteria can be analyzed by mass spectrometry. Here, we established bacSCP, a p...
Julia Leodolter, Tim Thierer, K. Mechtler et al.
· Nature Communications · 0 citations