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Author

Junjie Yao

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#protein folding Open access Sep 2026

A full-thickness spatial transcriptomics atlas of medically refractory ulcerative colitis identifies niche signatures associated with biologic non-response

Ulcerative colitis (UC) is a chronic mucosal immune disorder in which 30-50% of patients fail biologic therapy, yet the full-thickness immune architecture of medically refractory disease and reliable tissue-level markers of treatment response remain undefined. Using 10x Visium HD spatial transcriptomics (16-...

Qing-Quan Bai, Run-Yang Li, Zheng-Jin Liu et al. · 0 citations
Jul 2026

MERIT: Efficient In-Place Deletion for Dynamic Graph-Based Approximate Nearest Neighbor Indexes

Graph-based indexes have become the dominant approach to approximate nearest neighbor search (ANNS) over high-dimensional data and play a crucial role in real-world applications such as retrieval-augmented generation, recommendation systems, and vector databases. Despite extensive progress in static graph construction...

Ze-Kai Wu, Jiabao Jin, Peng Cheng et al. · 0 citations

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