Review
Open access
Aug 2026
The metastatic spectrum in functional and non-functional NENs: mechanistic insights from multi-omics
Neuroendocrine neoplasms (NENs) are biologically heterogeneous tumors in which differentiation/grade and hormonal functionality are intersecting but non-equivalent axes. This review focuses on functional and non-functional well-differentiated neuroendocrine tumors (NETs), principally gastroenteropancreatic and pancreat...
Zhengjian Wang, Xu-Da Ji, Zhe Wang et al.
· Frontiers in Endocrinology · 0 citations