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K. J. O’Byrne

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#protein folding Review Open access Aug 2026

The role of hSSB1 and hSSB2 in the DNA damage response: mechanisms and implications

The DNA damage response preserves genome integrity by detecting DNA lesions, activating checkpoint signalling, and coordinating repair with cell-cycle control. Defective or incomplete repair can promote mutation accumulation, chromosomal instability, cancer development, and ageing-associated diseases. In this review,...

Armin Sharifi, Amila Suraweera, K. J. O'Byrne et al. · 0 citations

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