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Katarina Akhmetova

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Open access Aug 2026

Metazoan Orc6 Proteins Evolved Alternative Mechanisms for Association with the ORC Complex: Insights from Drosophila Modeling

This study analyzed specific residues within the C-terminal α11 helix that are critical for stable association of Orc6 with the ORC complex in Drosophila and proposed that this NLS drives human protein to the nucleus and compensates for weaker Orc6-ORC(1-5) interactions by increasing the nuclear concentration of Orc6 a...

M. Balasov, Etsuko Shibata, Katarina Akhmetova et al. · 0 citations

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