Aug 2026
rs57494551 increases CXCR5 expression and IgM+ CXCR5+ B-cell infiltration in the portal area of primary biliary cholangitis.
Immune dysregulation and portal inflammation are affected by increased expression of CXCR5 on IgM+ B-cells in PBC patients who have the risk allele of rs57494551, indicating that CXCR5 is a potential therapeutic target for PBC.
Hitomi Yuki, Yoshihiro Aiba, Kazuko Ueno et al.
· Journal of gastroenterology · 0 citations