Author

Ke Pei

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Open access Oct 2026

Network Pharmacology-Assisted Multi-Omics Analysis of Gut Microbiota–Host Metabolic Remodeling and Hepatic HPD/GSTM3-Associated Redox Responses Following Shanqijing Treatment in STZ-Induced Diabetic Mice

Background/Objectives: Shanqijing (SQJ) is a multibotanical aqueous extract prepared from an equal-ratio blend of Astragali Radix, Dioscoreae Rhizoma, Corni Fructus, Polygonati Rhizoma, and Polygonati Odorati Rhizoma. This study investigated the pharmacological effects and systems-level response pattern of SQJ in strep...

Xiang-Peng Kong, Hai-Qin Ren, Jia-Ni He et al. · Pharmaceuticals · 0 citations

Aug 2026

Salvianolic acid a alleviates myocardial ischemia-reperfusion injury in rats via SIRT1-mediated inhibition of oxidative stress and inflammation.

SAA mitigates MIRI-induced oxidative stress and inflammation by activating SIRT1, which regulates the PGC-1α/Nrf2/HO-1 and NF-κB pathways, supporting SAA as a potential therapeutic agent for MIRI.

Zhen Chen, Yan-Ran Cao, Hao Bo et al. · International Immunopharmaco... · 0 citations