Molecular Characterization of Soritesidine Reveals a Novel Marine Sponge DNase I-like Toxin
Soritesidine (SOR) is a potent proteinaceous toxin from the marine sponge Spongosorites sp. that is toxic to mammalian cells, brine shrimp larvae, sea hare embryos, and mice. Although SOR exhibits divalent metal ion-dependent DNase activity, its molecular identity and mechanism of action remained unknown. We determined...
Hiromi Watari, Koji Nakano, M. Kitano et al.
· Toxins · 0 citations