CCNB1IP1 regulatory evolution underlies gradual increases in cortical size and folding in primates.
The gradual expansion and folding of the cortex are key factors in human cognitive evolution, yet their molecular underpinnings remain not well understood. Here we identify cyclin B1 interacting protein 1 (CCNB1IP1) gene as a key regulator of human brain evolution using tree shrew as an outgroup. In primates, CCNB1IP1...
Ting Hu, Peng-Cheng Ma, Yi-Fan Kong et al.
· Nature Genetics · 0 citations