AlphaPeptTools is presented, a Python package for the analysis of MS-proteomics data built on the AnnData data structure of the scverse, which implements scalable and modular strategies for MS-data ingestion, quality control, preprocessing, and statistical analysis while seamlessly integrating with the scverse ecosyste...
Vincenth Brennsteiner, L. Diedrich, S. Ben-Moshe et al.· bioRxiv· 0 citations
This work demonstrates an end-to-end analysis from raw images to statistical characterization of how cell type composition and spatial distribution vary across indolent and aggressive lymphomas and presents a Python-based toolbox that supports end-to-end analysis of highly multiplexed imaging data.
Matthias Meyer-Bender, Harald Vöhringer, C. Schniederjohann et al.· Nature Methods· 1 citation
A scalable technology is introduced that quantifies thousands of proteins and transcripts in the same cell, separating RNA from protein by tip-based C18 capture and pairing full-length RNA sequencing with latest-generation mass spectrometry to yield deep proteome and transcriptome from the same cells.
M. Thielert, Enes Ugur, Maximilian Zwiebel et al.· bioRxiv· 1 citation
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