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L. Lorefice

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#protein folding Open access Oct 2026

Salivary Proteomics Reveals Disease- and Therapy-Associated Molecular Patterns in Relapsing-Remitting Multiple Sclerosis

It is indicated that six months of therapy was associated with substantial salivary proteome changes and support saliva as a candidate biofluid for longitudinal molecular monitoring and non-invasive detection of treatment-associated salivary proteome variations in RRMS.

Giulia Guadalupi, C. Contini, Chiara Piras et al. · 0 citations
Review Oct 2026

When sex matters early: clues from pediatric onset multiple sclerosis.

Evidence from epidemiological, clinical, neuroimaging, biomarker, and therapeutic studies across prepubertal, peripubertal, and post-pubertal stages is synthesized to help elucidate the mechanisms driving these differences, refine early risk stratification, and support more individualized therapeutic strategies across...

L. Lorefice, R. Zivadinov · 0 citations
Open access Oct 2026

Top-Down CSF Peptidomics Reveals Disease-Associated Peptide Signatures and Oxidative Modifications in Multiple Sclerosis and Neuromyelitis Optica Spectrum Disorder.

Multiple sclerosis and neuromyelitis optica spectrum disorder (NMOSD) are inflammatory demyelinating diseases of the CNS whose diagnosis is mainly based on clinical evidence, magnetic resonance imaging, and the analysis of cerebrospinal fluid (CSF). Current approaches provide only partial insight into disease-related b...

C. Contini, L. Lorefice, Greca Lai et al. · 0 citations

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