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Author

L. Zentilin

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Open access Sep 2026

AAV-mediated SIL1 gene therapy prevents cerebellar degeneration and ataxia in a mouse model of Marinesco-Sjögren syndrome

Findings provide proof-of-principle that AAV-mediated SIL1 gene therapy can prevent the neurological and muscular manifestations of Marinesco-Sjögren syndrome and identify Purkinje cells as a critical cellular target for preventing cerebellar dysfunction.

Chiara Pasini, Giada Lavigna, Anna Grasso et al. · 0 citations
Sep 2026

The PSD-95 interactome of hippocampal synapses potentiated in response to an in vivo learning task

SynActive-PSD95-FLAG, a genetically encoded probe consisting of FLAG-tagged PSD- 95 endowed with activity-dependent local translation and expression enrichment at potentiating dendritic spines, provides new insight into the molecular substrates of hippocampal learning and a novel tool to study the proteome of potentiat...

A. Jacob, M. Di Caprio, I. Arisi et al. · 0 citations

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