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Lee Chuin Chen

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#protein folding Oct 2026

Cytochrome c is Highly Compact upon Transfer into the Gas Phase from Strong Acids as Revealed by High-Pressure ESI Ion Mobility-Mass Spectrometry

A substantial increase in the acidity of the protein solution (e.g., from pH 2 to pH 1) is known to induce the compaction of fully unfolded proteins, such as cytochrome c, into a non-native yet highly compact molten globule state, referred to as the A-state. In this study, the conformational landscape of the gaseous...

Shunsuke Kamioka, K. Ohshimo, D. Asakawa et al. · 0 citations

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