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Sponsored AI Networking Cookbook: Practical recipes for AI-assisted network automation and development AI Networking Cookbook: Practical recipes for AI-assisted network automation and development

Author

Lijuan Li

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#protein folding Open access Sep 2026

Engineered genomic attachment sites for site-specific recombinases enable high-efficiency integration in plants and human cells.

Here we developed a DNA-centric strategy for optimizing site-specific recombination by rationally engineering chimeric attachment sites. The high-activity att variants enhance Bxb1-mediated integration efficiency in human cells and plants. Among these att variants, the engineered attB(V111) site achieved 51.9% integrat...

Lin-Li Yan, Ling Zhou, Qiang Gao et al. · 0 citations
Review Open access Jul 2026

Beyond exhaustion: T cell fitness for next generation of immunotherapy for hematological cancer

T cell-directed immunotherapies have transformed the treatment of hematological malignancies, but durable benefit remains limited by relapse, poor persistence, incomplete immune reconstitution and infection. These outcomes depend not only on target-antigen expression but also on the functional quality of the T cell com...

Xiao-Shuang Kong, Yuan-Hui Su, Hanxue Zheng et al. · 0 citations

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