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Author

Li-Juan Zou

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Review Open access Jul 2026

GRP78 dysregulation: A proposed molecular mechanism linking the tumor microenvironment to sepsis susceptibility in patients with cancer (Review)

The hypothesis that GRP78 dysregulation may increase sepsis susceptibility through two convergent mechanisms is advanced, which provides a preliminary theoretical framework for future investigations into GRP78-mediated sepsis susceptibility in patients with cancer, with hypothetical implications for risk stratification...

Hang Ruan, Meipeng Zhu, Shi-Yan Liu et al. · 1 citation
Review Open access Feb 2026

Artificial intelligence-assisted phenotyping of sepsis: Research progress, clinical challenges, and translational prospects

This narrative review synthesizes recent advances in AI-assisted sepsis phenotyping, focusing on three persistent research bottlenecks: terminological inconsistency, fragmented integration between prognostic stratification and treatment-response phenotyping, and ambiguous clinical translation pathways.

Hang Ruan, Jing-Kun Lee, Jie Xiong et al. · 0 citations

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