Author

Liyan Miao

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#protein folding Open access Oct 2026

Longitudinal monitoring of adalimumab levels and anti-adalimumab antibodies in Chinese patients with ankylosing spondylitis: a prospective cohort study

This study aimed to clarify the association between longitudinal adalimumab concentrations, anti-adalimumab antibodies (AAA) levels, and clinical response in Chinese patients with ankylosing spondylitis (AS). A prospective multi-center, observational cohort study of AS patients receiving adalimumab therapy w...

Xiao-Liang Ding, Ling Xue, Ming-Jun Wang et al. · Frontiers in Immunology · 0 citations

Open access Sep 2026

Patient-derived organoids enable ex vivo drug-response profiling for precision medicine in bladder cancer

Patient-derived organoids (PDOs) represent a promising precision medicine approach for replicating primary tumor characteristics and facilitating drug testing across various cancers, although clinical evidence in bladder cancer remains limited. This study evaluates the impact of incorporating PDOs into clinical pract...

Si-Jia Li, Feng Qiu, Fang-Yue Zheng et al. · npj Precision Oncology · 0 citations

Jul 2026

A UHPLC-MS/MS method for the simultaneous quantification of BTK inhibitors and their active metabolite in human plasma and cerebrospinal fluid.

This method detects four BTK-related analytes in plasma/CSF with a 3-min run time, evaluation of hemolytic/lipemic matrices, and clinical validation, increasing throughput, reducing costs, and broadening applicability, providing preliminary feasibility data for clinical TDM.

Sijia Li, Jiameng Xie, F. Xia et al. · Bioanalysis · 0 citations