Sono-Tribocatalytic Whole Tumor Cell Vaccine Enables Ultrasound-Controlled Immune Boosting for Enhanced Anti-Tumor Immunity.
Whole tumor cell vaccines are uniquely positioned for personalized immunotherapy by presenting the full repertoire of tumor-associated antigens to counter tumor heterogeneity, yet their translation is persistently hindered by poor immunogenicity and the requirement for multiple administrations. Herein, we introduce a s...