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Open access Oct 2026

Population cellular kinetics and exposure-CSR analysis of CAR-T cells in Chinese patients with relapsed/refractory B-ALL

Background CD19-targeting chimeric antigen receptor (CAR)-T cells have demonstrated great efficacy in treating relapsed and refractory B-cell acute lymphoblastic leukemia (B-ALL). Despite the high objective response rate of CAR-T cell therapy, high-risk adverse event of cytokine-release syndrome occur unexpectedly. Obj...

Yi-Cong Bian, Jin-Jie Yuan, Chen-Rong Huang et al. · 0 citations
#protein folding Open access Oct 2026

Longitudinal monitoring of adalimumab levels and anti-adalimumab antibodies in Chinese patients with ankylosing spondylitis: a prospective cohort study

This study aimed to clarify the association between longitudinal adalimumab concentrations, anti-adalimumab antibodies (AAA) levels, and clinical response in Chinese patients with ankylosing spondylitis (AS). A prospective multi-center, observational cohort study of AS patients receiving adalimumab therapy w...

Xiao-Liang Ding, Ling Xue, Ming-Jun Wang et al. · 0 citations

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