SUGP1 Deficiency Leads to Splicing Dysregulation and Reduced piRNA Abundance in Insects
SUGP1 (SURP and G-patch domain containing 1) participates in splice-site recognition through its interaction with SF3B1, and loss of this factor leads to aberrant splicing. While its role in pre-mRNA splicing is well-documented, its impact on small RNA pathways remains poorly understood. Here, we used CRISPR/Cas9-media...
Dan Liu, Yongkang Guo, Liting Wang et al.
· Biology · 0 citations