Acrolein target-linked toxicological perturbation and tumor-immune microenvironment heterogeneity in colorectal cancer
Background Acrolein is a highly reactive aldehyde generated endogenously during lipid peroxidation and encountered through environmental and dietary exposures. Although acrolein has established electrophilic, genotoxic, and oxidative-stress effects, the extent to which acrolein-linked gene perturbation is represented i...