Abstract Genomic prediction has become a central paradigm in biology, enabling quantitative inference of genetic contributions to complex traits across humans, animals, and plants. Although genomic research in human genetics and animal breeding shares a highly homologous methodological foundation, significant barriers...
Jin-Bu Wang, Li-Li Du, Zhi-Da Zhao et al.· Briefings in Bioinformatics· 0 citations
Genome-wide association study (GWAS) analyses have identified numerous loci associated with economic traits in cattle. Many of these loci reside in noncoding regions, and the regulatory mechanisms through which they influence complex traits remain poorly understood. Here, we integrated 657 RNA-seq libraries from 275 Hu...
Shiyuan Qiu, Li-Li Du, Bo-Yu Zhang et al.· Genomics, Proteomics & Bioin...· 0 citations
Cell-resolved maps provide mechanistic insight into how genetic variation shapes economically important traits, offering a valuable resource for functional studies, cell-informed precision breeding strategies, and the design of large-scale molecular phenotyping.
Bo-Yu Zhang, Shiyuan Qiu, Zhen-Wei Du et al.· Journal of Animal Science an...· 0 citations