Accurate and efficient prediction of protein conformations with ProtMonomer
Deep learning-based protein structure prediction methods that leverage evolutionary information from multiple sequence alignments (MSAs), exemplified by AlphaFold2, have achieved remarkable accuracy. However, existing methods still struggle to predict challenging proteins, particularly those with novel folds or limited...
Yunda Si, Suqi Zhang, Luo-Nan Chen
· bioRxiv · 0 citations