Author

L. Davis

2 papers indexed here

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Aug 2026

A genome-wide map of the genetic network in monocytes that regulates type I interferon induction by the cGAS-STING pathway.

Type I interferons (IFNs) are induced by pattern recognition receptors (PRRs) of the innate immune system to protect against foreign pathogens and malignant transformation, and their production must be tightly regulated to balance antiviral defense with tissue homeostasis. To define the genetic network that governs IFN...

E. A. Thomsen, Jian Zhao, Ryo Narita et al. · Science Signaling · 0 citations

#protein folding Open access Aug 2026

β-strand addition within tip initiation complexes licenses assembly of diverse type IV filaments

How PilC/PilY1 can be retained on the fiber tip under enormous tensile loads generated during mechanical shear and T4P retraction is explained and how diverse T4P systems employ β-strand addition to license fiber assembly is demonstrated.

Taylor J. Ellison, Zoey R. Litt, Justin N. Applegate et al. · Proceedings of the National... · 0 citations