Alzheimer’s disease target and drug discovery by leveraging multiomics and electronic health data
Despite prolific genomic data from individuals with Alzheimer’s disease (AD), translation into treatments has lagged. Here we applied Mendelian randomization to multiple AD genome-wide association studies and functional multiomics datasets to nominate druggable targets, identifying 19 targets for individuals of Europea...
Yuan Hou, Yichen Li, Pengyue Zhang et al.
· Nature Neuroscience · 0 citations