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Author

M. A. Najar

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2 papers indexed here

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Sep 2026

Integrated Metabolomic, Proteomic, and Phosphoproteomic Profiling Reveals Metabolic and Signaling Alterations Associated with CAMKK2 Inhibition in Gastric Cancer

Gastric cancer is driven by aberrant kinase signaling that promotes uncontrolled proliferation and metabolic adaptations. Although calcium/calmodulin-dependent protein kinase 2 (CAMKK2) is overexpressed in gastric cancer, its role in regulating tumor-associated metabolic programs remains unclear. Here, we employed an...

M. A. Najar, Nikita Choudhary, Nidhi Dwivedi et al. · 0 citations
#protein folding Sep 2026

Systems-level proteomic reprogramming reveals mitochondrial restoration and inhibition of Rho GTPase-mediated cytoskeletal and inflammatory signaling in CKD

It is demonstrated that DVA exerts a dual therapeutic effect by restoring essential mitochondrial and metabolic pathways while simultaneously suppressing inflammation, oxidative stress, and cytoskeletal dysregulation in CKD.

Reshma Shettigar, Shobha Dagamajalu, Hemashree Kampa et al. · 0 citations

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