In the version of the article initially published, the graphs in Fig. 2a were missing and have now been reinserted in the HTML and PDF versions of the article.
Kyle J. Kinney, Kun Jia, He Zhang et al.
· Nature Communications · 0 citations
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2026
Kim A. Lennox, M. Behlke
· Methods in molecular biology · 0 citations
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Open access
Aug 2026
An in-cell method that sensitively detects rare off-target edits, benchmarks performance across editors, and improves risk assessment in therapeutic cells is presented, establishing UNCOVERseq as a robust framework for informed off-target risk assessment in translational gene-editing systems.
Kyle J. Kinney, Kun Jia, He Zhang et al.
· Nature Communications · 3 citations
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Open access
Aug 2026
It is shown that off-target editing and translocations vary widely between individual cells and organs, motivating the development of more sensitive and organ-specific safety assays for CRISPR therapies.
Alexandra Madsen, Niklas Selfjord, M. Martinez-Lage et al.
· Nature Communications · 0 citations
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