Open access
Sep 2026
Loss of function of LprG-Rv1410c and MmpL11 homologues in Mycobacterium smegmatis leads to altered glycopeptidolipid profile and decreased cellular c-di-GMP levels during biofilm formation
While both LprG-Rv1410c and MmpL11 pathways are involved in modulating cellular c-di-GMP levels during biofilm formation, only LprG-Rv1410c are important for regulating GPL synthesis and/or surface localization, and MmpL11 may play a broad role in fine-tuning GPL levels.
Mariah Desroches, M. Coldren, Lisa-Marie Nisbett
· bioRxiv · 0 citations