Rational mutagenesis reveals substrate-specific activity shifts in the Antarctic polyesterase MoPE.
Overall, this work demonstrates that rational mutagenesis can alter polyesterase activity against structurally distinct biodegradable polyesters, providing potential mechanistic insights to guide the development of specialized biocatalysts for targeted polyester degradation.
Konstantinos Makryniotis, Panagiota Karampa, M. Dimarogona et al.
· Enzyme and Microbial Technol... · 0 citations