Skip to content

Author

M. du Plessis

4 papers indexed here

We haven’t gathered this author’s papers yet. Follow them and we’ll fetch their work.

Not the right person? Other researchers publish under this name.

#protein folding Open access Oct 2026

Identifying candidate genetic determinants associated with invasion in pneumococcal lineages

This work conducted a species-wide genome-wide association study of invasion and compared the prevalence of significant unitigs in GPSC1 and GPSC21 to identify invasion-associated variants differentiating them, and highlighted candidate proteins that may help explain invasiveness and could be explored as vaccine antige...

M. Pesonen, O. Lorenz, M. du Plessis et al. · 0 citations
Open access Oct 2026

Antimicrobial resistance trends and lineage distribution among invasive pneumococcal disease isolates pre- and post-pneumococcal conjugate vaccine introduction, South Africa.

OBJECTIVES Pneumococcal conjugate vaccines (PCV) have reduced antimicrobial-resistant invasive pneumococcal disease (IPD) globally. We evaluated trends in antimicrobial-resistant IPD and pneumococcal lineages before and after PCV13 introduction in South Africa. METHODS We analysed national, laboratory-based IPD surve...

Cebile Lekhuleni, K. Ndlangisa, L. De Gouveia et al. · 0 citations
Review Open access Sep 2026

High Mortality in Adults With Community-Acquired Pneumonia Admitted to Hospitals in South Africa Before and During the COVID-19 Pandemic, Stratified by HIV Serostatus and Viral Load: Data From a Prospective Cohort Study (2019–2021)

In-hospital and postdischarge community-acquired pneumonia mortality remains high, particularly among PWH, regardless of virologic status, warranting urgent investigation of mitigation strategies.

N. Sabet, Firdaus Nabeemeeah, K. Otwombe et al. · 0 citations
Open access Sep 2026

Pneumococcal population structure influences the effects of air pollution on invasive disease risk in South Africa

Streptococcus pneumoniae is highly diverse, comprising over 100 serotypes and hundreds of genomic lineages amid widespread vaccination. While it can cause invasive pneumococcal disease (IPD) which exhibits pronounced seasonal spikes, the interplay between pneumococcal diversity and environmental drivers remains unexplo...

S. Belman, Cebile Lekhuleni, J. Kleynhans et al. · 1 citation

We use cookies to run the site and, with your consent, for analytics and to show ads. See our Cookie Policy.